| Bioactivity | Riboxin (IDP), an orally active purine derivative-hypoxanthine rlboside, has antihypoxic and antihyperthermic activity. Riboxin also has an antiarrhythmic action in cats, rabbits, and mice with cardiac rhythm disorders induced by Ouabain. Riboxin protects animals against the noxious effects of γ-irradiation[1][2]. |
| In Vivo | Riboxin (250 mg/kg; 口服; 单剂量) 可增加小鼠的游泳时间，但对力量耐力无显著影响。在相同条件下，Riboxin 提高了热室实验中动物的存活率[1]。Riboxin (50 mg/kg; 口服; 每天1次，持续6天) 增加小鼠游走的时间，而对游泳和跑步的时间无显著影响[1]。Riboxin (250 mg/kg; 口服; 实验前 1 小时) 对小鼠有明显的 γ 辐照保护作用[1]。 |
| Name | Riboxin |
| CAS | 86-04-4 |
| Formula | C9H12N4O11P2 |
| Molar Mass | 414.16 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sokolov I K, et al. Adaptogenic effect of riboxin[J]. Pharmaceutical Chemistry Journal, 1980, 14(1): 34-39. [2]. Veveris M, et al. Experimental study of the antiarrhythmic effect of riboxin. Farmakol. Neirotropnykh Sredstv (1978), 119-24. |