| Bioactivity | Raclopride is a dopamine D2/D3 receptor antagonist with potential antipsychotic effects. Raclopride binds to D2 and D3 receptors with Kis of 1.8 nM and 3.5 nM, respectively[1][2]. | ||||||||||||
| In Vivo | Raclopride (0.1, 0.3, or 0.6 mg/kg; IP; 30 min; albino male mice of the OF1 strain) significantly reduces time allocated to attack behavior[2]. | ||||||||||||
| Name | Raclopride | ||||||||||||
| CAS | 84225-95-6 | ||||||||||||
| Formula | C15H20Cl2N2O3 | ||||||||||||
| Molar Mass | 347.24 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Seeman P, et al. Dopamine receptor pharmacology. Trends Pharmacol Sci. 1994 Jul;15(7):264-70. [2]. Aguilar MA, et al. Behavioral profile of raclopride in agonistic encounters between male mice. Pharmacol Biochem Behav. 1994;47(3):753-756. |
Raclopride
CAS: 84225-95-6 F: C15H20Cl2N2O3 W: 347.24
Raclopride is a dopamine D2/D3 receptor antagonist with potential antipsychotic effects. Raclopride binds to D2 and D3 r
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