| Bioactivity | Rabies Virus Glycoprotein is a 29-amino-acid cell penetrating peptide derived from a rabies virus glycoprotein that can cross the blood-brain barrier (BBB) and enter brain cells. |
| Invitro | RVG peptide is successfully used to carry a variety of cargos into brain cells such as plasmids, siRNAs, proteins, and nanoparticles[1]. RVG29 can govern the interaction of viral particles with at least three known receptors, including neural cell adhesion molecule (NCAM), the p75 neurotrophin receptor (P75NTR), and nicotinic acetylcholine receptors (NAChRs). The RVG29 peptide enhances the brain-specific function of a range of systemically delivered agents, particularly nucleic acids[2]. |
| Name | Rabies Virus Glycoprotein |
| Sequence | Tyr-Thr-Ile-Trp-Met-Pro-Glu-Asn-Pro-Arg-Pro-Gly-Thr-Pro-Cys-Asp-Ile-Phe-Thr-Asn-Ser-Arg-Gly-Lys-Arg-Ala-Ser-Asn-Gly |
| Shortening | YTIWMPENPRPGTPCDIFTNSRGKRASNG |
| Formula | C141H217N43O43S2 |
| Molar Mass | 3266.70 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |