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ROS tracer precursor

CAS: 2153480-20-5 F: C39H45N3O8S W: 715.85

ROS tracer precursor is the precursor of ROStrace for the synthesis of ROStrace, which can be used for disease diagnosis
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Bioactivity ROS tracer precursor is the precursor of [18F]ROStrace for the synthesis of ROStrace, which can be used for disease diagnosis[1].
In Vivo [18F]ROStrace is a radiotracer for imaging superoxide in vivo with positron emission tomography (PET), in an LPS model of neuroinflammation. [18F]ROStrace is found to rapidly cross the blood-brain barrier (BBB) and is trapped in the brain of LPS-treated animals. [18F]ox-ROStrace, the oxidized form of [18F]ROStrace, does not cross the BBB. [18F]ROStrace is a suitable radiotracer for imaging superoxide levels in the central nervous system with PET[1].
Name ROS tracer precursor
CAS 2153480-20-5
Formula C39H45N3O8S
Molar Mass 715.85
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Hou C, et al. Development of a Positron Emission Tomography Radiotracer for Imaging Elevated Levels of Superoxide in Neuroinflammation. ACS Chem Neurosci. 2018 Mar 21;9(3):578-586.