Bioactivity | RB-OPD (NO-red) is a o-phenylenediamine (OPD)-locked rhodamine nitric oxide (NO) fluorescent probe with great sensitivity and selectivity (λex=550 nm, λem=590 nm)[1]. | ||||||||||||
Invitro | RB-OPD (compound 1) exhibits “turn-on” type fluorogenic and chromogenic behavior toward NO in aqueous solution with great sensitivity and selectivity, and it can be used for the sensing of NO under normal physiological conditions. NO-red is composed of two moieties: rhodamine B spirolactam as the potential strong fluorophore and chromophore, and o-phenylenediamine as an NO-reactive group in a lactam form as a “masked” NO-sensitive modulator[1]. | ||||||||||||
Name | RB-OPD | ||||||||||||
CAS | 1034863-51-8 | ||||||||||||
Formula | C34H36N4O2 | ||||||||||||
Molar Mass | 532.68 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Hong Zheng, et al. Fluorogenic and chromogenic rhodamine spirolactam based probe for nitric oxide by spiro ring opening reaction. Org Lett. 2008 Jun 19;10(12):2357-60. |