Bioactivity | Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction[1][2]. | ||||||||||||
Invitro | Quinolinic acid (0-50 mM; 24 hours) decreases the percentage of survival cells ranging from 100±0.01% at 5 mM to 45.23±0.01% at 50 mM in N18D3 cells[2]. Cell Viability Assay[2] Cell Line: | ||||||||||||
Name | Quinolinic acid | ||||||||||||
CAS | 89-00-9 | ||||||||||||
Formula | C7H5NO4 | ||||||||||||
Molar Mass | 167.12 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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