PeptideDB

Propiconazole

CAS: 60207-90-1 F: C15H17Cl2N3O2 W: 342.22

Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxic
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Bioactivity Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxicant and a hepatocarcinogen that has adverse reproductive and developmental toxicities in experimental animals[1][2].
In Vivo Propiconazole (150 mg/kg, 灌胃,给药14天) can induce specific hepatic P450 isoforms[1]. Animal Model:
Name Propiconazole
CAS 60207-90-1
Formula C15H17Cl2N3O2
Molar Mass 342.22
Appearance Oil
Transport Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Guobin Sun, et al. Propiconazole-induced cytochrome P450 gene expression and enzymatic activities in rat and mouse liver. Toxicol Lett. 2005 Feb 15;155(2):277-87. [2]. ShuangLi, et al. Single and Combined Cytotoxicity Research of Propiconazole and Nano-zinc Oxide on the NIH/3T3 Cell. Procedia Environmental Sciences Volume 18, 2013, Pages 100-105.