Bioactivity | Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxicant and a hepatocarcinogen that has adverse reproductive and developmental toxicities in experimental animals[1][2]. | ||||||||||||
In Vivo | Propiconazole (150 mg/kg, 灌胃,给药14天) can induce specific hepatic P450 isoforms[1]. Animal Model: | ||||||||||||
Name | Propiconazole | ||||||||||||
CAS | 60207-90-1 | ||||||||||||
Formula | C15H17Cl2N3O2 | ||||||||||||
Molar Mass | 342.22 | ||||||||||||
Appearance | Oil | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Guobin Sun, et al. Propiconazole-induced cytochrome P450 gene expression and enzymatic activities in rat and mouse liver. Toxicol Lett. 2005 Feb 15;155(2):277-87. [2]. ShuangLi, et al. Single and Combined Cytotoxicity Research of Propiconazole and Nano-zinc Oxide on the NIH/3T3 Cell. Procedia Environmental Sciences Volume 18, 2013, Pages 100-105. |