| Bioactivity | Promazine (Romtiazin) hydrochloride is an antipsychotic and a dopamine receptor D2 antagonist. Promazine hydrochloride inhibits dopaminergic neurotransmission[1][2]. |
| Invitro | Promazine hydrochloride shows KDs of 25, 190 and 8400 nM at the human norepinephrine transporter, serotonin transporter, and dopamine transporter, respectively[3]. |
| Name | Promazine hydrochloride |
| CAS | 53-60-1 |
| Formula | C17H21ClN2S |
| Molar Mass | 320.88 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Reference | [1]. Gareri P, et al. Conventional and atypical antipsychotics in the elderly : a review. Clin Drug Investig. 2003;23(5):287-322. [2]. Myers PR, et al. Characterization of a depolarizing dopamine response in a vertebrate neuronal somatic cell hybrid. J Cell Physiol. 1977;91(1):103-118. [3]. Tatsumi M, et al. Pharmacological profile of neuroleptics at human monoamine transporters. Eur J Pharmacol. 1999;368(2-3):277-283. |
Promazine hydrochloride
CAS: 53-60-1 F: C17H21ClN2S W: 320.88
Promazine (Romtiazin) hydrochloride is an antipsychotic and a dopamine receptor D2 antagonist.Promazine hydrochloride in
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