Bioactivity | Polyphemusin I is a natural antimicrobial peptide with excellent antimicrobial activity against Gram-negative and Gram-positive bacteria. Polyphemusin I contains 18 amino acids and is stabilized into an amphiphilic, antiparallel β-hairpin by two disulfide bridges[1]. |
Name | Polyphemusin I |
CAS | 125139-67-5 |
Sequence | Arg-Arg-Trp-Cys-Phe-Arg-Val-Cys-Tyr-Arg-Gly-Phe-Cys-Tyr-Arg-Lys-Cys-Arg-NH2 (Disulfide bridge:Cys4-Cys17,Cys8-Cys13) |
Shortening | RRWCFRVCYRGFCYRKCR-NH2 (Disulfide bridge:Cys4-Cys17,Cys8-Cys13) |
Formula | C108H161N39O20S4 |
Molar Mass | 2453.94 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Jon-Paul S Powers, et al. The antimicrobial peptide polyphemusin localizes to the cytoplasm of Escherichia coli following treatment. Antimicrob Agents Chemother. 2006 Apr;50(4):1522-4. |