PeptideDB

Polyphemusin I

CAS: 125139-67-5 F: C108H161N39O20S4 W: 2453.94

Polyphemusin I is a natural antimicrobial peptide with excellent antimicrobial activity against Gram-negative and Gram-p
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Polyphemusin I is a natural antimicrobial peptide with excellent antimicrobial activity against Gram-negative and Gram-positive bacteria. Polyphemusin I contains 18 amino acids and is stabilized into an amphiphilic, antiparallel β-hairpin by two disulfide bridges[1].
Name Polyphemusin I
CAS 125139-67-5
Sequence Arg-Arg-Trp-Cys-Phe-Arg-Val-Cys-Tyr-Arg-Gly-Phe-Cys-Tyr-Arg-Lys-Cys-Arg-NH2 (Disulfide bridge:Cys4-Cys17,Cys8-Cys13)
Shortening RRWCFRVCYRGFCYRKCR-NH2 (Disulfide bridge:Cys4-Cys17,Cys8-Cys13)
Formula C108H161N39O20S4
Molar Mass 2453.94
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Jon-Paul S Powers, et al. The antimicrobial peptide polyphemusin localizes to the cytoplasm of Escherichia coli following treatment. Antimicrob Agents Chemother. 2006 Apr;50(4):1522-4.