Bioactivity | Polidocanol is a sclerosing agent used successfully to treat extremity and esophageal varices and telangiectasias. | ||||||||||||
In Vivo | Polidocanol (0.5%, 1%, and 2%) results in significantly more adhesions than tetracycline, whereas the effect of diluted polidocanol is similar to that of tetracycline in rats. The higher concentrationsof polidocanol, of 0.5%, 1%, and 2% are more effective than either the diluted polidocanol or tetracycline against pleurodesis[1]. | ||||||||||||
Name | Polidocanol | ||||||||||||
CAS | 9002-92-0 | ||||||||||||
Formula | (C2H4O)nC12H26O | ||||||||||||
Appearance | Viscous liquid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
|
||||||||||||
Reference | [1]. Cetin B, et al. Polidocanol at different concentrations for pleurodesis in rats. Surg Today. 2005;35(12):1066-9. |