| Bioactivity | Pholedrine, the main metabolite of methamphetamine, is an indirectly acting sympathomimetic amine. Pholedrine is a cardiovascular agent exerting hypertensive and adrenergic effects. Pholedrine can produce mydriatic response and allow localization of the site of the interruption in the oculosympathetic pathway. Pholedrine can be used as a topical eye drop and a diagnostic agent for use in Horner's syndrome[1][2][3]. |
| Name | Pholedrine |
| CAS | 370-14-9 |
| Formula | C10H15NO |
| Molar Mass | 165.23 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Richard Bade, et al. Pholedrine is a marker of direct disposal of methamphetamine. Sci Total Environ. 2021 Aug 15;782:146839. [2]. A T Bates, et al. Pholedrine: a substitute for hydroxyamphetamine as a diagnostic eyedrop test in Horner's syndrome. J Neurol Neurosurg Psychiatry. 1995 Feb;58(2):215-7. [3]. Peinhardt GP. High-performance liquid chromatographic determination of pholedrine in human serum using ion-pair extraction and amperometric detection. J Chromatogr B Biomed Sci Appl. 1999 Apr 16;726(1-2):309-12. |