| Bioactivity | Peptide T (TFA) is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a ligand for the CD4 receptor and prevents binding of HIV to the CD4 receptor. |
| Invitro | Peptide T acts to block viral entry as it inhibits in the MAGI cell assay and blocks infection in the luciferase reporter assay using HIV virions pseudotyped with ADA envelope. Peptide T selectively inhibits HIV replication using chemokine receptor CCR5 compared to CXC4[2]. Peptide T at 10-8 M induces IL-10 production by the human Th2 cell line and PBMC. Also peptide T at 10-9 M concentration significantly inhibits IFN-g production by PBMC[3]. |
| Name | Peptide T TFA |
| CAS | 1610056-01-3 |
| Sequence | Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr |
| Shortening | ASTTTNYT |
| Formula | C37H56F3N9O18 |
| Molar Mass | 971.89 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Peptide T TFA
CAS: 1610056-01-3 F: C37H56F3N9O18 W: 971.89
Peptide T (TFA) is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a ligand for theCD4 receptor and preve
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