| Bioactivity | Oxolinic acid is an antibiotic against both Gram-negative and Gram-positive bacteria. Oxolinic acid can be used for the research of acute and chronic urinary tract infections. Oxolinic acid is a DNA/RNA synthesis inhibitor. Oxolinic acid acts a dopamine uptake inhibitor and stimulants locomotor effect in mice[1][2][3]. | ||||||||||||
| Invitro | Oxolinic acid (2-5 ug/mL) inhibits 115 strains of E. coli[1].Oxolinic acid (0-31 ug/mL) inhibits 94 % of the 44 strains of Proteus mirabilis [1].Oxolinic acid (>5 ug/mL) inhibits all strains of Strept. Faecalis[1].Oxolinic acid (>2 ug/mL) causes chromosomal DNA supercoiling to decrease in the two wild-type E. coli K-12 strains tested, DM4100 and NI747[2].Oxolinic acid reduces chromosomal DNA supercoiling and inhibits RNA synthesis in E. coli[2]. | ||||||||||||
| Name | Oxolinic acid | ||||||||||||
| CAS | 14698-29-4 | ||||||||||||
| Formula | C13H11NO5 | ||||||||||||
| Molar Mass | 261.23 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Oxolinic acid
CAS: 14698-29-4 F: C13H11NO5 W: 261.23
Oxolinic acid is an antibiotic against both Gram-negative and Gram-positive bacteria. Oxolinic acid can be used for the
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