| Bioactivity | Ovalbumin is a native protein with full length. This protein is purified from chicken egg white. Its purity was determined by SDS-PAGE and reached up to 95%. It is presented the mass molecule around 45 kDa visualized on the gel. It has been validated in ELISA, WB and SDS-PAGE applications. |
| Invitro | TAP1-I- and C57BL/6 macrophages may process Crl-OVA and full-length OVA in different cellular compartments and that the protein context of the OVA Peptide epitope influences the extent of TAP-independent processing for MHC class I presentation. OVA Peptide epitope is presented with a differential dependence on the TAP transporter depending on the protein context of the OVA epitope: OVA Peptide contained within the MBPCrl-OVA or Crl-OVA bacterial fusion proteins is presented with little dependence on the TAP transporter, while OVA Peptide contained within full-length ovalbumin is largely dependent on the TAP transporter, regardless of whether recombinant OVA is expressed in bacteria or the native protein is coupled to polystyrene beads[1]. |
| Name | OVA Peptide |
| Synonyms | L-seryl-L-isoleucyl-L-isoleucyl-L-asparaginyl-L-phenylalanyl-L-a-glutamyl-L-lysyl- L-Leucine trifluoroacetate, OVA (257 - 264), SIINFEKL trifluoroacetate salt, Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu trifluoroaceate, pOV8 |
| CAS | 138831-86-4 |
| Sequence | Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu |
| Shortening | SIINFEKL |
| Formula | C45H74N10O13 · xC2HF3O2 |
| Molar Mass | 963.13 |
| InChI | 1S/C45H74N10O13.C2HF3O2/c1-7-25(5)36(55-44(66)37(26(6)8-2)54-38(60)28(47)23-56)43(65)52-32(22-34(48)57)42(64)51-31(21-27-14-10-9-11-15-27)41(63)50-30(17-18-35(58)59)40(62)49-29(16-12-13-19-46)39(61)53-33(45(67)68)20-24(3)4;3-2(4,5)1(6)7/h9-11,14-15,24-26,28-33,36-37,56H,7-8,12-13,16-23,46-47H2,1-6H3,(H2,48,57)(H,49,62)(H,50,63)(H,51,64)(H,52,65)(H,53,61)(H,54,60)(H,55,66)(H,58,59)(H,67,68);(H,6,7)/t25-,26-,28-,29-,30-,31-,32-,33-,36-,37-;/m0./s1 |
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| Use | Ovalbumin chicken has been used to trigger T cell activation in immunology studies.
Ovalbumin chicken has been used:
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| Physical and Chemical Properties | Ovalbumin chicken is an antigenic peptide and triggers immune response.[5] Administration of the ovalbumin peptide in pregnant mice helps in surpassing ear development anomalies.[6] SIINFEKL is a class I (Kb)-restricted peptide epitope of ovalbumin (OVA); the ovalbumin fragment is presented by the class I MHC molecule, H-2Kb. |
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| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Ovalbumin Peptide
CAS: 138831-86-4 F: C45H74N10O13 · xC2HF3O2 W: 963.13
Ovalbumin (OVA) is the main protein found in egg white proteins (EWP),which has good functionality, particularly foaming
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