Osteocalcin (1-49) (human)_product_DataBase

Bioactivity	Osteocalcin (1-49) (human) is a vitamin K-dependent bone specific protein. Osteocalcin (1-49) (human) is chemotactic for several of the cell types frequently found at bone remodeling surfaces[1][2].
Invitro	Up to 20% of all non-collagenous protein in human bone consists of Osteocalcin. Only minor amounts of Osteocalcin are secreted into the blood circulation where it can be measured by immunochemical methods[1].Osteocalcin in serum is supposedly derived from newly synthesized bone, and the amount of this protein in serum may be a very specific marker for bone formation rate[1].Osteocalcin (1 nM-1 μM) is chemotactic for breast cancer cells and osteoblast-like osteogenic sarcoma cells as well as monocytes, and causes their unidirectional migration[2]. Osteocalcin peptide contains 49 amino acids, with subsequent breakdown to fragments 1–19, 20–49, 20–43, 1–43, and 44–49 in the liver, kidney, and serum[3].
Name	Osteocalcin (1-49) (human)
CAS	136461-80-8
Shortening	YLYQWLGAPVPYPDPL-{Gla}-PRR-{Gla}-VC-{Gla}-LNPDCDELADHIGFQEAYRRFYGPV (Disulfide bridge:Cys23-Cys29)
Formula	C269H381N67O82S2
Molar Mass	5929.44
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

PeptideDB