| Bioactivity | Neurodazine is a neurogenic inducer, serve as a promoter of neurogenesisin pluripotent cells. Neurodazine promotes neurogenesis by activating Wnt and Shh signaling pathways.[1][2]. | ||||||||||||
| Invitro | Neurodazine (5 μM; 1-10 d) treatment induces the expression of neuron-specific markers in P19 cells[1].Neurodazine selectively suppresses astrocyte differentiation of P19 cells[1]. Western Blot Analysis[1] Cell Line: | ||||||||||||
| Name | Neurodazine | ||||||||||||
| CAS | 937807-66-4 | ||||||||||||
| Formula | C27H21ClN2O3 | ||||||||||||
| Molar Mass | 456.92 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Kim GH, et al. Imidazole-based small molecules that promote neurogenesis in pluripotent cells. Angew Chem Int Ed Engl. 2014 Aug 25;53(35):9271-4. [2]. Halder D, et al. Synthetic small molecules that induce neuronal differentiation in neuroblastoma and fibroblast cells. Mol Biosyst. 2015 Oct;11(10):2727-37. |
Neurodazine
CAS: 937807-66-4 F: C27H21ClN2O3 W: 456.92
Neurodazine is a neurogenic inducer, serve as a promoter of neurogenesisin pluripotent cells. Neurodazine promotes neuro
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