Bioactivity | Nasunin, an antioxidant anthocyanin, possesses antiangiogenic activity[1]. |
Invitro | Nasunin at higher 10 µM suppresses microvessel outgrowth in an ex vivo angiogenesis assay using a rat aortic ring[1].Nasunin suppresses HUVEC proliferation in a dose-dependent manner (50-200 µM)[1].Nasunin diminishes LPS-induced nuclear factor-κB (NF-κB) activation by suppressing thedegradation of inhibitor of κB-α and nuclear translocation of p65 subunit of NF-κB. Nasunin also attenuates the phosphorylation of Akt and p38, signaling molecules involved in pro-inflammatory mediator production[1]. |
Name | Nasunin |
CAS | 28463-30-1 |
Formula | C42H47ClO23 |
Molar Mass | 955.26 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |