| Bioactivity | Nandrolone decanoate (19-Nortestosterone decanoate), an anabolic androgenic steroid (AAS), induces an aggressive phenotype by mechanisms involving glutamate-induced N-methyl-d-aspartate receptor (NMDAr) hyperexcitability[1]. Nandrolone decanoate has beneficial effects on weight, lean body mass and quality of life in selected patients who have mild to moderate HIV wasting[2]. | ||||||||||||
| Target | Androgen Receptor | ||||||||||||
| In Vivo | Long-term Nandrolone decanoate exposure (15 mg/kg) induces an exacerbated aggressive behavior in CF1 male mice[1]. Animal Model: | ||||||||||||
| Name | Nandrolone decanoate | ||||||||||||
| CAS | 360-70-3 | ||||||||||||
| Formula | C28H44O3 | ||||||||||||
| Molar Mass | 428.65 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Eduardo Kalinine, et al. Nandrolone-induced aggressive behavior is associated with alterations in extracellular glutamate homeostasis in mice. Horm Behav. 2014 Jul;66(2):383-92. [2]. J Gold, et al. Safety and efficacy of nandrolone decanoate for treatment of wasting in patients with HIV infection. AIDS. 1996 Jun;10(7):745-52. |