PeptideDB

N-Butanoyl-L-homoserine lactone

CAS: 67605-85-0 F: C8H13NO3 W: 171.19

N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (AD
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Bioactivity N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm[1]. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[2][3].
Invitro The dissociation constant (Kd value) of aptamer binding to N-Butanoyl-L-homoserine lactone (C4-HSL) is 28.47 nM[2].
Name N-Butanoyl-L-homoserine lactone
CAS 67605-85-0
Formula C8H13NO3
Molar Mass 171.19
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month