| Bioactivity | Methylprednisolone acetate, a prednisolone derivative, is a corticosteroid hormone. Methylprednisolone acetate can relieve pain and swelling that occurs with arthritis and other joint disorders in vivo[1][2]. | ||||||||||||
| In Vivo | Methylprednisolone acetate (30 mg/kg, intramuscular injection; additional oral doses of 13 mg/kg for 10 consecutive days)combines with LPS induces typical features of early AVN of the femoral head[2]. Animal Model: | ||||||||||||
| Name | Methylprednisolone acetate | ||||||||||||
| CAS | 53-36-1 | ||||||||||||
| Formula | C24H32O6 | ||||||||||||
| Molar Mass | 416.51 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Ha Thi -Ngan Le, et al. A mouse model of osteonecrotic femoral head induced by methylprednisolone and liposaccharide. Biomedical Research and Therapy volume 3, Article number: 12 (2016) [2]. Luis M Franco,et al. Immune regulation by glucocorticoids can be linked to cell type-dependent transcriptional responses. J Exp Med. 2019 Feb 4;216(2):384-406. |