Metaraminol tartrate_product_DataBase

Bioactivity	Metaraminol tartrate (Metaradrine tartrate) is an α-adrenergic agonist[1]. Metaraminol tartrate is a sympathomimetic amine that directly and indirectly affects adrenergic receptors, with alpha effects being predominant.Metaraminol tartrate acts as a vasopressor agent[2].
Target	Adrenergic Receptor
Invitro	Stimulation of α-adrenoceptors by metaraminol, a drug with properties similar to noradrenaline, caused acceleration of cell proliferation in colonie crypts but not in tumors[3].
In Vivo	Lethal endotoxin shock is prevented in six of the 10 animals studied by the simultaneous use of Metaraminol[2]. Animal Model:
Name	Metaraminol tartrate
CAS	33402-03-8
Formula	C13H19NO8
Molar Mass	317.29
Appearance	Solid
Transport	Room temperature in continental US; may vary elsewhere.
Storage	4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Reference	[1]. C Tong, et al. The vascular mechanism of ephedrine's beneficial effect on uterine perfusion during pregnancy. Anesthesiology. 1992 May;76(5):792-8. [2]. WESLEY W. SPINK, et al. Evaluation of Plasma, Metaraminol, and Hydrocortisone in Experimental Endotoxm Shock. [3]. P J Tutton, D H Barkla. The influence of adrenoceptor activity on cell proliferation in colonic crypt ipithelium and in colonic adenocarcinomata. Virchows Arch B Cell Pathol. 1977 Jun 24;24(2):139-46.

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