| Bioactivity | MRS 1754 is a selective antagonist radioligand for A2B adenosine receptor with very low affinity for A1 and A3 receptors of both humans and rats[1]. | ||||||||||||
| Target | A2B Adenosine Receptor | ||||||||||||
| Invitro | The most potent displacer of [3H]MRS 1754 binding is MRS 1754. The Ki value for displacement of [3H]MRS 1754 binding to human A2B receptors expressed in HEK-293 cell membranes is 1.45±0.21 nM[1]. | ||||||||||||
| Name | MRS 1754 | ||||||||||||
| CAS | 264622-58-4 | ||||||||||||
| Formula | C26H26N6O4 | ||||||||||||
| Molar Mass | 486.52 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Ji X, et al. [3H]MRS 1754, a selective antagonist radioligand for A(2B) adenosine receptors. Biochem Pharmacol. 2001 Mar 15;61(6):657-63. |