| Bioactivity | Loperamide (hydrochloride) (R-18553 (hydrochloride)) is an opioid receptor agonist[1][2][3]. Loperamide hydrochloride is a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor. Loperamide hydrochloride has anti-diarrheal effect[4]. |
| Name | Loperamide hydrochloride |
| CAS | 34552-83-5 |
| Formula | C29H34Cl2N2O2 |
| Molar Mass | 513.50 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Hanauer, S.B., The role of loperamide in gastrointestinal disorders. Rev Gastroenterol Disord, 2008. 8(1): p. 15-20. [2]. Litovitz, T., et al., Surveillance of loperamide ingestions: an analysis of 216 poison center reports. J Toxicol Clin Toxicol, 1997. 35(1): p. 11-9. [3]. http://www.drugs.com/mmx/loperamide-hydrochloride.html [4]. Hatfield MJ, et al. Carboxylesterase inhibitors. Expert Opin Ther Pat. 2011 Aug;21(8):1159-71. |
Loperamide hydrochloride
CAS: 34552-83-5 F: C29H34Cl2N2O2 W: 513.50
Loperamide (hydrochloride) (R-18553 (hydrochloride)) is an opioid receptor agonist. Loperamide hydrochloride is a select
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