| Bioactivity | Liquiritin (Standard) is the analytical standard of Liquiritin. This product is intended for research and analytical applications. Liquiritin, a flavonoid isolated from Glycyrrhiza uralensis, is a potent and competitive AKR1C1 inhibitor with IC50s of 0.62 μM, 0.61 μM, and 3.72μM for AKR1C1, AKR1C2 and AKR1C3, respectively. Liquiritin efficiently inhibits progesterone metabolism mediated by AKR1C1 in vivo[1]. Liquiritin acts as an antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity[2]. |
| Target | IC50: 0.62 μM (AKR1C1), 0.61 μM (AKR1C2) and 3.72μM (AKR1C3) |
| CAS | 551-15-5 |
| Formula | C21H22O9 |
| Molar Mass | 418.39 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zeng C, et al. Liquiritin, as a Natural Inhibitor of AKR1C1, Could Interfere With the Progesterone Metabolism. Front Physiol. 2019 Jul 3;10:833. [2]. Nakatani Y, et al. Neuroprotective effect of liquiritin as an antioxidant via an increase in glucose-6-phosphate dehydrogenase expression on B65 neuroblastoma cells. Eur J Pharmacol. 2017 Nov 15;815:381-390. |
Liquiritin (Standard)
CAS: 551-15-5 F: C21H22O9 W: 418.39
Liquiritin (Standard) is the analytical standard of Liquiritin. This product is intended for research and analytical app
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This product is for research use only, not for human use. We do not sell to patients.