Bioactivity | Lipopolysaccharides (LPS) is a class of specific endotoxins that constitute one of the major components of the cell wall in Gram-negative bacteria. LPS is composed of three components: Lipid A, the core oligosaccharide, and the O-specific polysaccharide. LPS is a powerful immune stimulant capable of activating the host immune system, particularly by binding to the Toll-like receptor 4 (TLR4) on the surface of immune cells, which triggers an inflammatory response. This product is derived from Salmonella enterica of the Minnesota serotype. Lipopolysaccharides can be utilized in studies concerning the activation of the host immune system and its role in inflammation and immune regulation[1]. |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Olsthoorn M M A, et al. Identification of a Novel Core Type in SalmonellaLipopolysaccharide: COMPLETE STRUCTURAL ANALYSIS OF THE CORE REGION OF THE LIPOPOLYSACCHARIDE FROM SALMONELLA ENTERICA sv. ARIZONAE O62[J]. Journal of Biological Chemistry, 1998, 273(7): 3817-3829. |