| Bioactivity | L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex. | ||||||||||||
| Invitro | L-Tyrosine inhibits citrate synthase activity in the posterior cortex (2.0 and 4.0 mM), malate dehydrogenase is not altered by L-Tyrosine and succinate dehydrogenase is increased in the posterior cortex (0.1-4.0 mM), hippocampus (1.0-4.0 mM), striatum (4.0 mM) and liver (0.1-4.0 mM). When complex I activity is analyzed, inhibition is observed in hippocampus (4.0 mM). In addition to inhibition in the hippocampus, complex II also is inhibited in the posterior cortex (0.1-4.0 mM) and liver (1.0, 2.0 and 4.0 mM). For complex II–III, activity is not altered by L-Tyrosine, and complex IV activity has decreased in the posterior cortex (1.0-4.0 mM) following treatment with L-Tyrosine[1]. | ||||||||||||
| Name | L-Tyrosine | ||||||||||||
| CAS | 60-18-4 | ||||||||||||
| Formula | C9H11NO3 | ||||||||||||
| Molar Mass | 181.19 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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