| Bioactivity | L-Palmitoylcarnitine, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2[1]. | ||||||||||||
| Invitro | L-Palmitoylcarnitine (1 µM) inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2. L-Palmitoylcarnitine simultaneously enhances the ATP sensitivity of the channel (IC50 fell from 62 to 30 µM)[1].Modulation of the membrane lipid environment caused by L-Palmitoylcarnitine alters the KATP channel function mainly through the interaction with endogenous PI cascade, especially PIP2[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> L-Palmitoylcarnitine 相关抗体: | ||||||||||||
| CAS | 2364-67-2 | ||||||||||||
| Formula | C23H45NO4 | ||||||||||||
| Molar Mass | 399.61 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
||||||||||||
| Reference | [1]. Haruna T, et al. Alteration of the membrane lipid environment by L-palmitoylcarnitine modulates K(ATP) channels in guinea-pig ventricular myocytes. Pflugers Arch. 2000;441(2-3):200-207. |
L-Palmitoylcarnitine
CAS: 2364-67-2 F: C23H45NO4 W: 399.61
L-Palmitoylcarnitine, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.