Bioactivity | L,L-Dityrosine (o,o'-Dityrosine) is a constituent of acid hydrolysates of a number of biological materials, including the insect cuticular resilin[1]. |
In Vivo | L,L-Dityrosine (o,o'-Dityrosine) is elevated in ventral midbrain and striatum of MPTP-treated mice[2]. |
Name | L,L-Dityrosine |
CAS | 63442-81-9 |
Formula | C18H20N2O6 |
Molar Mass | 360.36 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
Reference | [1]. Kungl AJ, et al. Molecular dynamics simulation of the rare amino acid LL-dityrosine and a dityrosine-containing peptide: comparison with time-resolved fluorescence. Biochim Biophys Acta. 1994 Dec 15;1201(3):345-52. [2]. S Pennathur, et al. Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease. J Biol Chem. 1 |