| Bioactivity | Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A1 (A1R) and A2A (A2AR) receptors[1][2][3]. | ||||||||||||
| Invitro | Inosine dose-dependently stimulates cAMP production mediated through the A2AR[2].Inosine dose-dependently induces hA2AR-mediated ERK1/2 phosphorylation[2].Inosine (100 μM; 24 hours) reduces oxidative stress in MES 23.5 cells cultured with astrocytes[3]. | ||||||||||||
| Name | Inosine | ||||||||||||
| CAS | 58-63-9 | ||||||||||||
| Formula | C10H12N4O5 | ||||||||||||
| Molar Mass | 268.23 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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