| Bioactivity | Indecainide hydrochloride is a potent and orally active class I local anesthetic antiarrhythmic agent[1]. |
| In Vivo | Indecainide hydrochloride (0, 3, 6, or 9 mg/kg; IV, daily for 1 month) causes 6 of 10 male rats and 1 of 10 female rats die at 9 mg/kg during the test period[2].Indecainide hydrochloride (0, 1.5, 3, or 4.5 mg/kg; IV, daily for 1 month) causes 2 of 4 dogs die at 4.5 mg/kg; exhibits no overt signs of toxicity and no hematologic, serum chemistry or histologic changes at 1.5 or 3 mg/kg[2]. |
| Name | Indecainide hydrochloride |
| CAS | 73681-12-6 |
| Formula | C20H25ClN2O |
| Molar Mass | 344.88 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Steinberg MI, et al. Electrophysiological studies of indecainide hydrochloride, a new antiarrhythmic agent, in canine cardiac tissues. J Cardiovasc Pharmacol. 1984 Jul-Aug;6(4):614-21. [2]. Sandusky GE Jr, et al. Toxicology of indecainide hydrochloride after intravenous administration to rats and dogs. Toxicol Lett. 1985 Aug;26(2-3):107-10. |