Indacrinone

CAS: 56049-88-8 F: C18H14Cl2O4 W: 365.21

Indacrinone (MK196) is an investigational diuretic which has pronounced saluretic activity in the rat and dog as well as

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Bioactivity	Indacrinone (MK196) is an investigational diuretic which has pronounced saluretic activity in the rat and dog as well as both uricosuric and saluretic activity in the chimpanzee.
In Vivo	As the dose increasing from 1 to 10 mg/kg, the amount excreted via the urine decreased from 20 to 11% of administered dose. The amount excretes via the feces is 2-fold higher at the lower dose. At the 10 mg/kg dose the Indacrinone (MK-196)/1 ratio is 0.8 and 5 for the urine and feces, respectively. The urinary ratio of Indacrinone/1 decrease as dose increasing from 10 mg/kg (0.5) to 20 mg/kg (0.2)[1].
Name	Indacrinone
CAS	56049-88-8
Formula	C18H14Cl2O4
Molar Mass	365.21
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. A.G. ZACCHEI, et al. THE PHYSIOLOGICAL DISPOSITION