| Bioactivity | Imidocarb is a potent antiprotozoal agent. Imidocarb is active against the parasite B. bovis with an IC50 of 87 μg/mL[1]. |
| In Vivo | Imidocarb dipropionate is administered by subcutaneous or intramuscular injection to horses (3.4 mg/kg bw) and cattle (2.I mg/kg bw). In horses, up to 4 doses may be given at 72-hour intervals. A second dose may be given 2 weeks after the first. Imidocarb dipropionate is also used in sheep (1. 2mg/kg bw) for the treatment of babesiosis and anaplasmosis. The acute oral LD50 value of Imidocarb dipropionate is in the range of 646 to 723 mg/kg bw in mice. The acute oral LD50 value of Imidocarb is in the range of 454 to 1251 mg/kg bw in rats. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| CAS | 27885-92-3 |
| Formula | C19H20N6O |
| Molar Mass | 348.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Rodriguez RI, et al. In vitro responsiveness of Babesia bovis to Imidocarb dipropionate and the selection of a drug-adapted line. Vet Parasitol. 1996 Mar;62(1-2):35-41. |