| Bioactivity | Ilimaquinone, a marine sponge metabolite, displays anticancer activity via GADD153-mediated pathway. Ilimaquinone can induce vesiculation of the Golgi apparatus[1]. Ilimaquinone exerts anti-HIV, anti-microbial, anti-inflammatory, and effects[2]. | |||||||||
| Invitro | Ilimaquinone induces a concentration-dependent anti-proliferative effect in several types of cancer cell lines, including prostate cancer PC-3 and LNCaP, non-small cell lung cancer A549 and hepatocellular carcinoma Hep3B cells. Ilimaquinone (0.3-30 μM; 48 hours) inhibits the proliferation of PC-3 cells, DU145, LNCaP, MG63, A549, Hep3B cells with GI50s of 2.6 μM, 5.8, 4.6, 4.9, 4.1, 12.0μM, respectively[1]. Cell Viability Assay[1] Cell Line: | |||||||||
| Name | Ilimaquinone | |||||||||
| CAS | 71678-03-0 | |||||||||
| Formula | C22H30O4 | |||||||||
| Molar Mass | 358.47 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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Ilimaquinone
CAS: 71678-03-0 F: C22H30O4 W: 358.47
Ilimaquinone, a marine sponge metabolite, displays anticancer activity via GADD153-mediated pathway.Ilimaquinone can ind
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