| Bioactivity | IDR-HH2 is an immunomodulatory peptide with the ability to modulate the host cytokine/chemokine environment. IDR-HH2 can promote the adhesion of monocytes and THP-1 cells to fibronectin. Additionally, IDR-HH2 possesses antibacterial activity, inhibiting the activity of both P. aeruginosa and S. aureus with MIC values of 75 µg/mL and 38 µg/mL, respectively[1][2]. |
| CAS | 1214699-22-5 |
| Sequence | Val-Gln-Leu-Arg-Ile-Arg-Val-Ala-Val-Ile-Arg-Ala-NH2 |
| Shortening | VQLRIRVAVIRA-NH2 |
| Formula | C62H117N23O13 |
| Molar Mass | 1392.74 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Madera L, et al. Synthetic immunomodulatory peptide IDR-1002 enhances monocyte migration and adhesion on fibronectin[J]. Journal of innate immunity, 2012, 4(5-6): 553-568. [2]. Rivas-Santiago B, et al. Ability of innate defence regulator peptides IDR-1002, IDR-HH2 and IDR-1018 to protect against Mycobacterium tuberculosis infections in animal models[J]. PloS one, 2013, 8(3): e59119. |
IDR-HH2
CAS: 1214699-22-5 F: C62H117N23O13 W: 1392.74
IDR-HH2 is an immunomodulatory peptide with the ability to modulate the host cytokine/chemokine environment. IDR-HH2 can
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