| Bioactivity | Hydroxydione has an effect of general anesthetic. Hydroxydione is a neuroactive steroid it can be used for anaesthesia related research[1][2]. |
| In Vivo | Hydroxydione increases the duration of hexobarbital narcosis and repeats hexobarbital doses decrease the duration of hydroxydione narcosis[1].Hydroxydione (5-100 mg/kg; i.v. once) produces a transient hypotension with little bradycardia and affects the respiration[2]. Animal Model: |
| Name | Hydroxydione |
| CAS | 303-01-5 |
| Formula | C21H32O3 |
| Molar Mass | 332.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. RUMKE CL. The influence of drugs on the duration of hexobarbital and hydroxydione narcosis in mice. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1963;244:519-30. [2]. LERMAN LH, PATON WD. Experiments on the pharmacology of hydroxydione sodium succinate. Br J Pharmacol Chemother. 1960 Sep;15(3):458-65. |