Bioactivity | Homopropargylglycine is a Methionine (HY-13694) analogue. Homopropargylglycine is incorporated at a suitable rate into newly synthesized proteins in a variety of systems, including mammalian cell culture. Homopropargylglycine can be used to identify old and new protein populations[1]. | ||||||||||||
Invitro | Homopropargylglycine enables Bio-Orthogonal Non-Canonical Amino acid Tagging (BONCAT) of a small sample of the proteins being synthesized in Arabidopsis plants or cell cultures, facilitating their click-chemistry enrichment for analysis[1]. | ||||||||||||
Name | Homopropargylglycine | ||||||||||||
CAS | 215160-72-8 | ||||||||||||
Formula | C6H9NO2 | ||||||||||||
Molar Mass | 127.14 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Tivendale ND, Millar AH, et al. In vivo homopropargylglycine incorporation enables sampling, isolation and characterization of nascent proteins from Arabidopsis thaliana. Plant J. 2021 Aug;107(4):1260-1276. |