| Bioactivity | Hexylresorcinol (4-Hexylresorcinol) is a natural compound found in plants with antimicrobial, anthelmintic, antiseptic and antitumor activities. Hexylresorcinol can induce apoptosis in squamous carcinoma cells. Hexylresorcinol is a reversible and noncompetitive inhibitor of α-glucosidase. Hexylresorcinol has protective effects against oxidative DNA damage[1][2][3][4][5]. | ||||||||||||
| Invitro | Hexylresorcinol potently inhibits Gram positive bacteria, with MICs of 20-50 mg/L for several Gram positive bacteria. Gram negative bacteria, yeasts and fungi are less sensitive to it[1].Hexylresorcinol inhibits oxidative DNA damage in human lymphocytes by increasing levels of glutathione and modulation of antioxidant enzymes (GPX, GR and GST)[2].Hexylresorcinol (1-10 µg/mL; 24-72 hours) suppresses squamous carcinoma cell line SCC-9 proliferation[3].Hexylresorcinol has strong antitumor effects by inhibiting calcium channel oscillation and inducing apoptosis[3].Hexylresorcinol upregulates TGF-β/SMAD/VEGF signaling in endothelial cells and induces vascular regeneration and remodeling for wound healing[5]. Cell Proliferation Assay[3] Cell Line: | ||||||||||||
| Name | Hexylresorcinol | ||||||||||||
| CAS | 136-77-6 | ||||||||||||
| Formula | C12H18O2 | ||||||||||||
| Molar Mass | 194.27 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Hexylresorcinol
CAS: 136-77-6 F: C12H18O2 W: 194.27
Hexylresorcinol (4-Hexylresorcinol) is a natural compound found in plants with antimicrobial, anthelmintic, antiseptic a
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