| Bioactivity | Hepcidin-1 (mouse) is an endogenous peptide hormone involved in the regulation of iron homeostasis. Hepcidin-1 (mouse) upregulates mRNA levels of TRAP, cathepsin K, and MMP-9 and increases TRAP-5b protein secretion. Hepcidin-1 (mouse) downregulates the level of FPN1 protein and increases intracellular iron. Hepcidin-1 (mouse) facilitates osteoclast differentiation[1]. |
| Name | Hepcidin-1 (mouse) |
| CAS | 1676104-75-8 |
| Sequence | Asp-Thr-Asn-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Lys-Cys-Cys-Asn-Asn-Ser-Gln-Cys-Gly-Ile-Cys-Cys-Lys-Thr (Disulfide bridge: Cys7-Cys23,Cys10-Cys22,Cys11-Cys19,Cys13-Cys14) |
| Shortening | DTNFPICIFCCKCCNNSQCGICCKT (Disulfide bridge: Cys7-Cys23,Cys10-Cys22,Cys11-Cys19,Cys13-Cys14) |
| Formula | C111H169N31O35S8 |
| Molar Mass | 2754.24 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhao GY, et al. Effects of mouse hepcidin 1 treatment on osteoclast differentiation and intracellular iron concentration. Inflammation. 2015 Apr;38(2):718-27. |
Hepcidin-1 (mouse)
CAS: 1676104-75-8 F: C111H169N31O35S8 W: 2754.24
Hepcidin-1 (mouse) is an endogenous peptide hormone involved in the regulation of iron homeostasis. Hepcidin-1 (mouse) u
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