PeptideDB

Haloperidol hydrochloride

CAS: 1511-16-6 F: C21H24Cl2FNO2 W: 412.33

Haloperidol hydrochloride is a potent dopamine D2 receptor antagonist, widely used as an antipsychotic.
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Bioactivity Haloperidol hydrochloride is a potent dopamine D2 receptor antagonist, widely used as an antipsychotic.
In Vivo Haloperidol (1 mg) intra-arterially attenuates the dopamine-induced pancreatic secretion. Haloperidol (3 mg) completely inhibits the action of 10 μg of dopamine in the pancreas of the dogs[1]. Haloperidol (10 mg/kg) as well as chlorpromazine (CPZ, 15 mg/kg) blocks mescaline-induced altered behavior within 7 to 10 minutes when injected into the mice 45 minutes after 50 mg/kg (2 µc) of mescaline. Haloperidol has no effect on mescaline disappearance[2].
Name Haloperidol hydrochloride
CAS 1511-16-6
Formula C21H24Cl2FNO2
Molar Mass 412.33
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Joy CB, et al. Haloperidol versus placebo for schizophrenia. Cochrane Database Syst Rev. 2006 Oct 18;(4):CD003082. [2]. Giannini AJ, et al. Acute ketamine intoxication treated by haloperidol: a preliminary study. Am J Ther. 2000 Nov;7(6):389-91.