| Bioactivity | Halofenozide (RH-0345) is an ecdysteroid agonist. RH-0345 belongs to a new group of insect growth regulators (IGRs) with a benzoylhydrazine structure that mimic the action of the natural insect molting hormone 20-hydroxyecdysone[1]. |
| Invitro | Halofenozide (RH-0345) reduces both growth and development of oocytes in vitro[1]. Cell Viability Assay[2] Cell Line: |
| In Vivo | After topical application of Halofenozide (RH-0345; 5 and 10 μg) on adult females, the highest dose (10 μg) reduces significantly the reproductive parameters scored: namely the oviposition period, the fecundity and the egg viability[1].Halofenozide at the two doses tested (5 and 10 μg) causes smaller eggs with a decrease in length, width and volume[1]. Animal Model: |
| Name | Halofenozide |
| CAS | 112226-61-6 |
| Formula | C18H19ClN2O2 |
| Molar Mass | 330.81 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Faïza Taïbi, et al. Effect of ecdysone agonist RH-0345 on reproduction of mealworm, Tenebrio molitor. Comp Biochem Physiol C Toxicol Pharmacol. 2003 Jul;135C(3):257-67. |
Halofenozide
CAS: 112226-61-6 F: C18H19ClN2O2 W: 330.81
Halofenozide (RH-0345) is an ecdysteroid agonist. RH-0345 belongs to a new group of insect growth regulators (IGRs) with
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