| Bioactivity | Halenaquinone is a phosphatidylinositol 3-kinase inhibitor and can be isolated from the marine sponge Petrosia alfiani. Halenaquinone inhibits RANKL (HY-P7424)-induced osteoclastogenesis, and induces cell apoptosis in PC12 cells[1][2][3]. |
| CAS | 86690-14-4 |
| Formula | C20H12O5 |
| Molar Mass | 332.31 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Deborah M. Roll, et al. Halenaquinone, a pentacyclic polyketide from a marine sponge. ：Journal of the American Chemical Society.Vol 105/Issue 19. [2]. Tsukamoto S, et al. Halenaquinone inhibits RANKL-induced osteoclastogenesis. Bioorg Med Chem Lett. 2014;24(22):5315-5317. [3]. Fujiwara H, et al. Halenaquinone, a novel phosphatidylinositol 3-kinase inhibitor from a marine sponge, induces apoptosis in PC12 cells. Eur J Pharmacol. 2001;413(1):37-45. |
Halenaquinone
CAS: 86690-14-4 F: C20H12O5 W: 332.31
Halenaquinone is a phosphatidylinositol 3-kinase inhibitor and can be isolated from the marine sponge Petrosia alfiani.
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