| Bioactivity | HKOCl-4m is a selective and mitochondria-targeting rhodol-based fluorescent probe for monitoring mitochondrial hypochlorous acid (HOCl)[1]. |
| Invitro | HKOCl-4m (5 µM; 30 min) exhibits robust increase in fluorescence intensity upon addition of HOCl. HKOCl-4m has been successfully applied in detecting endogenous HOCl in RAW264.7 mouse macrophages. HKOCl-4m could be applied for monitoring the mitochondrial HOCl formation in living cells[1]. |
| Name | HKOCl-4m |
| CAS | 2031170-88-2 |
| Formula | C63H61BrCl2N3O7P |
| Molar Mass | 1153.96 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Xiaoyu Bai, et al. HKOCl-4: a rhodol-based yellow fluorescent probe for the detection of hypochlorous acid in living cells and tissues. Org. Chem. Front, 2020. |