| Bioactivity | Guanadrel is an orally active postganglionic adrenergic inhibitor of spiroketal. Guanadre can be used in anti-hypertensive studies[1]. |
| In Vivo | Guanadrel (oral gavage, 15-400 mg/kg, every day, 6-52 weeks) has little toxicity to the nervous system in rats and dogs[1]. Animal Model: |
| Name | Guanadrel |
| CAS | 40580-59-4 |
| Formula | C10H19N3O2 |
| Molar Mass | 213.28 |
| Appearance | Oil |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. J D Palmer, et al. Guanadrel sulfate: a postganglionic sympathetic inhibitor for the treatment of mild to moderate hypertension. Pharmacotherapy. 1983 Jul-Aug;3(4):220-9. doi: 10.1002/j.1875-9114.1983.tb03257.x. |