Bioactivity | Glycyrrhetic acid 3-O-β-D-glucuronide, isolated from glycyrrhiza, is an important derivative of glycyrrhizin (GL) with an anti -allergic activity[1]. Glycyrrhetic acid 3-O-β-D-glucuronide (GAMG) shows that β‐glucuronidases (β‐GUS) are key GAMG-producing enzymes, displaying a high potential to convert GL directly into GAMG[2].Glycyrrhetic acid 3-O-β-D-glucuronide is valuable as a sweetener. | |||||||||
Invitro | Glycyrrhetic acid 3-O-β-D-glucuronide can inhibit the release of β‐hexosaminidase from RBL‐2H3 cells with an IC50 value of 0.28 mM[2].Glycyrrhetic acid 3-O-β-D-glucuronide (GAMG) significantly reduces the nitrite concentration in a dose-dependent manner with an IC50 value of 120 μM in LPS‐induced RAW264.7 cells[2]. | |||||||||
Name | Glycyrrhetic acid 3-O-β-D-glucuronide | |||||||||
CAS | 34096-83-8 | |||||||||
Formula | C36H54O10 | |||||||||
Molar Mass | 646.81 | |||||||||
Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
Storage |
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