PeptideDB

Garenoxacin

CAS: 194804-75-6 F: C23H20F2N2O4 W: 426.41

Garenoxacin (BMS284756) is an orally active quinolone antibiotic and has a broad spectrum of activity against a wide arr
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Bioactivity Garenoxacin (BMS284756) is an orally active quinolone antibiotic and has a broad spectrum of activity against a wide array of gram-positive and gram-negative bacteria, anaerobes, and fastidious organisms[1].
Invitro Garenoxacin (BMS284756) (0-8 days) inhibits mycoplasmas and ureaplasmas with MIC90s ≤0.25 μg/mL against tested strains[1].Garenoxacin (48 h) inhibits S. aureus wild type and mutants with MICs of 0.0128-4.0 μg/mL[2].Garenoxacin inhibits topoisomerase IV and gyrase from S. aureus with IC50s of 1.25 to 2.5 and 1.25 μg/mL, respectively[2].Garenoxacin has a low propensity for selective enrichment of fluoroquinolone-resistant mutants among ciprofloxacin-susceptible isolates of S. aureus[3]. Cell Viability Assay[1] Cell Line:
Name Garenoxacin
CAS 194804-75-6
Formula C23H20F2N2O4
Molar Mass 426.41
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.