| Bioactivity | Gadolinium chloride is a specific calcium-sensing receptor (CaSR) agonist. Gadolinium chloride can be used for the research of cardiovascular disease[1]. | ||||||||||||
| Target | CaSR | ||||||||||||
| Invitro | Gadolinium chloride (30 μM; 15 minutes; H9c2 cells) results in increased Bax expression and caspase-3 activation, and decreased Bcl-2 expression in CsA-induced cells[1].In vitro, GdCl3, a CaSR agonist, has been shown to promote the apoptosis of myocardial cells, which increases ERK1/2 phosphorylation and activates caspase-3[1]. Western Blot Analysis[1] Cell Line: | ||||||||||||
| Name | Gadolinium chloride | ||||||||||||
| CAS | 10138-52-0 | ||||||||||||
| Formula | Cl3Gd | ||||||||||||
| Molar Mass | 263.61 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Li X, et al. Calcium Oxalate Induces Renal Injury through Calcium-Sensing Receptor. Oxid Med Cell Longev. 2016;2016:5203801. |
Gadolinium chloride
CAS: 10138-52-0 F: Cl3Gd W: 263.61
Gadolinium chloride is a specific calcium-sensing receptor (CaSR) agonist. Gadolinium chloride can be used for the resea
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