| Bioactivity | GPI-1485 (GM1485), a nonimmunosuppressive immunophilin ligand, promotes neurofunctional improvement and neural regeneration following stroke[1]. | ||||||||||||
| Invitro | GPI-1485 (GM1485; 100 μM) induces cellular reprogramming and neural cell induction in normal human dermal fibroblasts (NHDF)[1]. Cell Viability Assay[1] Cell Line: | ||||||||||||
| In Vivo | GPI-1485 (GM1485; 5 mg/kg; intraperitoneal injection; 6-week period of daily) improves long-term neurological recovery in rats[1]. Animal Model: | ||||||||||||
| Name | GPI-1485 | ||||||||||||
| CAS | 186268-78-0 | ||||||||||||
| Formula | C12H19NO4 | ||||||||||||
| Molar Mass | 241.28 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Andrew F Ducruet , et al. GM1485, a Nonimmunosuppressive Immunophilin Ligand, Promotes Neurofunctional Improvement and Neural Regeneration Following Stroke. J Neurosci Res. 2012 Jul;90(7):1413-23. |