Fura-2 pentapotassium_product_DataBase

Bioactivity	Fura-2 pentapotassium is a scaled fluorescent dye that can be used for intracellular calcium imaging with the Kd value of 140 nM. Fura-2 pentapotassium has an emission wavelength of 510 nm and excitation wavelengths of 340 nm or 380 nm and the ratio of 340/380 fluorescence intensity is proportional to the intracellular Ca2+ level[1][2].
Invitro	Fura-2 pentapotassium (10 μM, 2 min) can be used to detect changes in the concentration of calcium ions in neutrophils of heparinized peripheral blood[1].Fura-2 pentapotassium (10 μM, 5 min) can be used as a calcium probe to assess the distribution of calcium ions within heart mitochondria without affecting the activity of it in rat[2].
Name	Fura-2 pentapotassium
CAS	113694-64-7
Formula	C29H22K5N3O14
Molar Mass	831.99
Appearance	Solid
Transport	Room temperature in continental US; may vary elsewhere.
Storage	-20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Reference	[1]. Omar Rafael Alemán, et al. The Antibody Receptor Fc Gamma Receptor IIIb Induces Calcium Entry via Transient Receptor Potential Melastatin 2 in Human Neutrophils. Front Immunol. 2021 May 13;12:657393. doi: 10.3389/fimmu.2021.657393. [2]. James G. McCormack, et al. Studies on mitochondrial Ca2+-transport and matrix Ca2+ using fura-2-loaded rat heart mitochondria. Biochim Biophys Acta. 1989 Mar 23;973(3):420-7.

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