Folitixorin

Bioactivity Folitixorin (5,10-methylenetetrahydrofolate) is a cofactor and an analog of leucovorin. Folitixorin is a promising agent for modulation of 5-FU cytotoxicity in adjuvant cancer research[1][2].
Invitro 5,10-methylenetetrahydrofolate reductase (MTHFR) catalyzes the conversion of 5,10-methylenetetrahydrofolate into 5-methyltetrahy-drofolate, which is the major circulating form of folate[3]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Name Folitixorin
CAS 3432-99-3
Formula C20H23N7O6
Molar Mass 457.44
Transport Room temperature in continental US; may vary elsewhere.
Storage

-80°C, protect from light, stored under nitrogen

Folitixorin (5,10-methylenetetrahydrofolate) is a cofactor and an analog of leucovorin. Folitixorin is a promising agent for modulation of 5-FU cytotoxicity in adjuvant cancer research.

 

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