Folitixorin (5,10-methylenetetrahydrofolate) is a cofactor and an analog of leucovorin. Folitixorin is a promising agent for modulation of 5-FU cytotoxicity in adjuvant cancer research.
| Bioactivity | Folitixorin (5,10-methylenetetrahydrofolate) is a cofactor and an analog of leucovorin. Folitixorin is a promising agent for modulation of 5-FU cytotoxicity in adjuvant cancer research[1][2]. |
| Invitro | 5,10-methylenetetrahydrofolate reductase (MTHFR) catalyzes the conversion of 5,10-methylenetetrahydrofolate into 5-methyltetrahy-drofolate, which is the major circulating form of folate[3]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| Name | Folitixorin |
| CAS | 3432-99-3 |
| Formula | C20H23N7O6 |
| Molar Mass | 457.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -80°C, protect from light, stored under nitrogen |
Folitixorin (5,10-methylenetetrahydrofolate) is a cofactor and an analog of leucovorin. Folitixorin is a promising agent for modulation of 5-FU cytotoxicity in adjuvant cancer research.