| Bioactivity | Fenipentol (1-Phenyl-1-pentanol), a synthetic derivative of an ingredient of Curcuma longa that is used as a condiment and dye. Fenipentol is also an orally active choleretic agent that plays an important role in release of secretin, gastrin, and pancreatic secretion of bicarbonate and protein[1][2][3]. |
| In Vivo | Fenipentol (PHP) (50-200 mg/kg; p.o. and intraduodenal administration) increases the secretory volume of pancreatic juice and the output of protein in rats[2].Fenipentol (50-200 mg/kg for i.p. and 5-10 mg/kg for i.v.) considerably increases biliary secretion in rats[2].Fenipentol (25-200 mg/kg; intraduodenal administration) stimulates the pancreatic secretion in the canine[2]. |
| Name | Fenipentol |
| CAS | 583-03-9 |
| Formula | C11H16O |
| Molar Mass | 164.24 |
| Appearance | Liquid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Fregnan GB, et, al. Therapeutic properties of dihydroxy-dibutylether on sub-acute liver damage induced by several hepatotoxic agents in rats. Int J Tissue React. 1982; 4(4): 309-18. [2]. Wakabayashi T, et, al. [Effect of 1-phenyl-1-hydroxy-n-pentane on pancreatic secretion in the rat and the dog]. Nihon Yakurigaku Zasshi. 1971 Nov; 67(6): 637-47. [3]. Sharma A, et, al. Biocatalytic and electrochemical reduction of selected phenyl alkanones with antibacterial activity of the corresponding phenyl alkanols. Ijabpt Com, 2011. |